Publications
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Ramachandran A, Basu U, Sultana S, Nandakumar D, Patel SS.
Human mitochondrial transcription factors TFAM and TFB2M work synergistically in promoter melting during transcription initiation.
Nucleic Acids Res. 2016 Nov 29. PMID:27903899
Chang HW, Pandey M, Kulaeva OI, Patel SS, Studitsky VM.
Overcoming a nucleosomal barrier to replication.
Sci Adv. 2016 Nov 11;2(11):e1601865. PMID:27847876
Brennan LD, Forties RA, Patel SS, Wang MD.
DNA looping mediates nucleosome transfer.
Nat Commun. 2016 Nov 3;7:13337. PMID:27808093
Ramachandran A, Nandakumar D, Deshpande A, Lucas TP, Bhojappa RR, Tang GQ, Raney K, Yin YW, Patel SS.
The yeast mitochondrial RNA polymerase and transcription factor complex catalyzes efficient priming of DNA synthesis on single-stranded DNA.
J Biol Chem. 2016 Jun 16. PMID:27311715
Nandakumar D, Patel SS.
Methods to study the coupling between replicative helicase and leading-strand DNA polymerase at the replication fork.
Methods. 2016 May 9. S1046-2023(16)30126-8. Review. PMID:27173619
Sen D, Patel G, Patel SS.
Homologous DNA strand exchange activity of the human mitochondrial DNA helicase TWINKLE.
Nucleic Acids Res. 2016 May 19;44(9):4200-10. PMID:26887820
Szymanski MR, Kuznetsov VB, Shumate C, Meng Q, Lee YS, Patel G, Patel S, Yin YW.
Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase.
EMBO J. 2015 Jul 14;34(14):1959-70. PMID:26056153
Sun B, Pandey M, Inman JT, Yang Y, Kashlev M, Patel SS, Wang MD.
T7 replisome directly overcomes DNA damage.
Nat Commun. 2015 Dec 17;6:10260. doi: 10.1038/ncomms10260.PMID:26675048
Devarkar SC, Wang C, Miller MT, Ramanathan A, Jiang F, Khan AG, Patel SS, Marcotrigiano J.
Structural basis for m7G recognition and 2'-O-methyl discrimination in capped RNAs by the innate immune receptor RIG-I.
Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):596-601. PMID:26733676
Ramanathan A, Devarkar SC, Jiang F, Miller MT, Khan AG, Marcotrigiano J, Patel SS.
The autoinhibitory CARD2-Hel2i Interface of RIG-I governs RNA selection.
Nucleic Acids Res. 2016 Jan 29;44(2):896-909. PMID:26612866
Pandey M, Elshenawy MM, Jergic S, Takahashi M, Dixon NE, Hamdan SM, Patel SS.
Two mechanisms coordinate replication termination by the Escherichia coli Tus-Ter complex.
Nucleic Acids Res. 2015 Jul 13;43(12):5924-35. PMID:26007657
Nandakumar D, Pandey M, Patel SS.
Cooperative base pair melting by helicase and polymerase positioned one nucleotide from each other.
Elife. 2015 May 13;4. doi: 10.7554/eLife.06562. PMID: 25970034
Nandakumar D, Patel SS.
Finding the right match fast.
Cell. 2015 Feb 26;160(5):809-11. doi: 10.1016/j.cell.2015.02.007.PMID:25723158
Deshpande AP, Patel SS.
Interactions of the yeast mitochondrial RNA polymerase with the +1 and +2 promoter bases dictate transcription initiation efficiency.
Nucleic Acids Res. 2014 Oct;42(18):11721-32.PMID:25249624
Deshpande AP, Sultana S, Patel SS.
Fluorescent methods to study transcription initiation and transition into elongation.
EXS. 2014;105:105-30. Review. PMID:25095993
Tang GQ, Nandakumar D, Bandwar RP, Lee KS, Roy R, Ha T, Patel SS.
Relaxed rotational and scrunching changes in P266L mutant of T7 RNA polymerase reduce short abortive RNAs while delaying transition into elongation.
PLoS One. 2014 Mar 20;9(3):e91859. PMID:24651161
Pandey M, Patel SS.
Helicase and polymerase move together close to the fork junction and copy DNA in one-nucleotide steps.
Cell Rep. 2014 Mar 27;6(6):1129-38. PMID:24630996
Syed S, Pandey M, Patel SS, Ha T.
Single-molecule fluorescence reveals the unwinding stepping mechanism of replicative helicase.
Cell Rep. 2014 Mar 27;6(6):1037-45. PMID:24630993
